Wakisaka Y, Nakatani T, Anai H, Araki K, Taenaka Y, Tatsumi E, Masuzawa T, Baba Y, Eya K, Toda K
Department of Artificial Organs, National Cardiovascular Center Research Institute, Osaka, Japan.
ASAIO J. 1995 Jul-Sep;41(3):M584-7.
From an engineering point of view, the suitable revolution number for high efficiency operation of an axial flow pump is known. A multistage axial flow pump is a useful tool for reducing revolution number with a high efficiency axial flow pump. A two stage (25) axial flow pump designed at a 5 L/min flow rate and a 100 mmHg pressure head was evaluated in three kinds of in vitro hemolysis tests. Each stage design point of the 2s pump was tested at a 5 L/min flow rate and a 50 mmHg pressure head. Specific speed and revolution number of the 2S pump were 1400 rpm, m3/min, m, and 15500 rpm, respectively. In the first test the 2S pump was compared with two single stage axial flow pumps (1S-A and 1S-B100) designed by the same method. The specific speed of the 1A was the same as that of the 2S pump, which was driven at 26000 rpm. The impeller of the 1S-B100 was the same as that of the 2S pump, which was driven at a 22000 rpm RN and a 1100 specific speed. The 2S pump was separated into two single stage axial flow pumps and the effect of series operation on hemolysis was evaluated in the second test. In the third test the 2S pump was compared with the 1S-B100 by using diluted goat blood samples with three different hematocrit values. The results showed that the hemolysis index of the 2S pump, regarded as a total hemolysis index of both stage axial flow pumps, was less than those of the single stage axial flow pumps at all hematocrit values.
从工程学角度来看，轴流泵高效运行时的合适转速是已知的。多级轴流泵是一种利用高效轴流泵降低转速的有用工具。一台设计流量为5升/分钟、压头为100毫米汞柱的两级（25）轴流泵在三种体外溶血试验中进行了评估。2s泵的每个级设计点在流量为5升/分钟、压头为50毫米汞柱的条件下进行测试。2S泵的比转速和转速分别为1400转/分钟、立方米/分钟、米和15500转/分钟。在第一次试验中，将2S泵与两台采用相同方法设计的单级轴流泵（1S - A和1S - B100）进行了比较。1A的比转速与2S泵相同，2S泵以26000转/分钟的转速驱动。1S - B100的叶轮与2S泵相同，以22000转/分钟的转速和1100的比转速驱动。在第二次试验中，将2S泵拆分为两台单级轴流泵，并评估了串联运行对溶血的影响。在第三次试验中，使用三种不同血细胞比容值的稀释山羊血样本将2S泵与1S - B100进行了比较。结果表明，2S泵的溶血指数（视为两级轴流泵的总溶血指数）在所有血细胞比容值下均低于单级轴流泵。
