Pollard G W, Marsh P L, Fife C E, Smith L R, Vann R D
Department of Physical Education, North Carolina State University, Raleigh, USA.
Undersea Hyperb Med. 1995 Dec;22(4):367-76.
The effects of ascent rate and post-dive exercise on the incidence of decompression sickness (DCS) were investigated in six groups of 20 rats exposed for 2 h at a pressure equivalent to 240 feet of sea water (fsw; 735 kPa). Ascent rates were 30, 45, and 60 fsw/min (92, 138, 184 kPa/min), and the rats either rested after the exposure or exercised by walking for 30 min on a treadmill at 1.6 m/min. Post-dive signs included respiratory distress, difficulty walking, paralysis, and death. DCS was scored as non-fatal at 30-min post-dive or fatal at any time. Analysis by ordinal logistic regression indicated more DCS with post-dive exercise (P = 0.0112) and at 45 (P = 0.0011) and 60 fsw/min (P = 0.0001) compared to 30 fsw/min. Survival analysis suggested earlier death at 60 fsw/min compared to 30 fsw/min (P = 0.0006). Similar effects have been reported for the less severe DCS that occurs in humans.
在六组每组20只大鼠中，研究了上升速率和潜水后运动对减压病（DCS）发病率的影响。这些大鼠在相当于240英尺海水深度（fsw；735千帕）的压力下暴露2小时。上升速率分别为30、45和60英尺/分钟（92、138、184千帕/分钟），暴露后大鼠要么休息，要么在跑步机上以1.6米/分钟的速度行走30分钟进行运动。潜水后的体征包括呼吸窘迫、行走困难、瘫痪和死亡。DCS在潜水后30分钟时被评为非致命或在任何时间被评为致命。序数逻辑回归分析表明，与30英尺/分钟相比，潜水后运动（P = 0.0112）以及45（P = 0.0011）和60英尺/分钟（P = 0.0001）时DCS更多。生存分析表明，与30英尺/分钟相比，60英尺/分钟时死亡更早（P = 0.0006）。对于人类发生的较轻的DCS也有类似的影响报道。
