加拿大白种人中的科尔顿血型：频率、遗传及连锁分析。

Colton blood groups in Canadian Caucasians: frequencies, inheritance and linkage analysis.

作者信息

Lewis M, Kaita H, Chown B, Giblett E R, Anderson J

出版信息

Vox Sang. 1977;32(4):208-13. doi: 10.1111/j.1423-0410.1977.tb00631.x.

DOI:10.1111/j.1423-0410.1977.tb00631.x

Abstract

In a series of 726 random Caucasian adults tested with anti-Coa and anti-Cob allele frequencies were Coa 0.9470, Cob 0.0530. The distribution of Colton phenotypes in 205 children of 57 selected families was in accordance with expectation. A linkage analysis of Co and 26 other loci indicates that Co is not closely linked to AcP1, ABO, AK1, Ch, Do, GLO, Gm, GPT, HLA, Hp, K, Lu, MN, PGM1 or Rh and does not lie between PGD and PGM1 on chromosome 1.

摘要

在对726名随机选取的高加索成年人进行检测的系列研究中，抗Coa和抗Cob等位基因频率分别为Coa 0.9470、Cob 0.0530。在57个选定家庭的205名儿童中，科尔顿血型表型的分布符合预期。对Co及其他26个基因座的连锁分析表明，Co与AcP1、ABO、AK1、Ch、Do、GLO、Gm、GPT、HLA、Hp、K、Lu、MN、PGM1或Rh没有紧密连锁，且不在1号染色体上的PGD和PGM1之间。