Beck O A, Hochrein H
Z Kardiol. 1977 Apr;66(4):187-90.
In 565 patients with acute myocardial infarction admitted to a coronary care unit within 12 hours of the onset of symptoms, serum potassium level was determined on admission. The incidence of dysrhythmias occurring during the first 12 hours was referred to the initial serum potassium level. Hypopotassemia (less than or equal to 3.5 mmol/l) was seen in 9.2% and associated with a significantly higher incidence of ventricular arrhythmias in 33% as compared to 18% in the control group. Especially ventricular fibrillation was significantly more frequent in the hypokalaemic (14%) than in the normokalaemic (3%) patients (P less than 0.01). Hyperpotassemia (less than or equal to 5.1 mmol/l) was found in 6% with a higher incidence of second and third degree AV block and left-bundle branch block. This group was much more prone to severe haemodynamic complications and therefore had a bad prognosis with a high clinic mortality of 53%. There was no relation between supraventricular arrhythmias, sinuatrial bradyarrhythmias and intraventricular block other than left bundle branch block to serum potassium level.
在症状发作12小时内入住冠心病监护病房的565例急性心肌梗死患者中,入院时测定血清钾水平。将最初12小时内发生心律失常的发生率与初始血清钾水平相关联。低钾血症(小于或等于3.5 mmol/L)的发生率为9.2%,与室性心律失常的发生率显著较高相关,低钾血症组为33%,而对照组为18%。特别是低钾血症患者发生心室颤动的频率(14%)明显高于正常血钾患者(3%)(P<0.01)。高钾血症(大于或等于5.1 mmol/L)的发生率为6%,二度和三度房室传导阻滞及左束支传导阻滞的发生率较高。该组更容易发生严重的血流动力学并发症,因此预后不良,临床死亡率高达53%。除左束支传导阻滞外,室上性心律失常、窦性缓慢性心律失常和室内传导阻滞与血清钾水平无关。