Mattern R M, Heck E L, Cavanagh H D
Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas 75235-9057, USA.
Cornea. 1995 Nov;14(6):562-7.
To determine how frequently specular microscopy results affect the outcome of eye-bank judgments on the transplantability of donor corneas, 1,011 consecutive donor records from a 3-year period at the Transplant Services Center of the University of Texas Southwestern Medical Center at Dallas were analyzed. Specular microscopy cell counts from each decade of donor age were determined, and it was found that there were no cell counts < 2,000 mm2 for any donor age < 40. Above age 40, the percentage of cell counts < 2,000 per mm2 rose from 3.9% for donors in their forties of 6% for donors in their seventies. For donors between 40 and 69 years, specular microscopy was used to rule out unacceptable tissue in an additional 3.3% of a prescreened pool of corneas evaluated by current Eye Bank Association of America standards. While corneas from donors over age 69 were initially presumed to be unacceptable for transplant at this eye bank, routine specular microscopic examination helped to clear for transplant of 31 corneas from donors of this age group.
为了确定角膜内皮显微镜检查结果对眼库关于供体角膜移植适用性判断结果的影响频率，对达拉斯德克萨斯大学西南医学中心移植服务中心3年期间连续的1011份供体记录进行了分析。确定了每个十年供体年龄的角膜内皮显微镜细胞计数，发现对于任何年龄小于40岁的供体，细胞计数均不低于2000/mm²。40岁以上，细胞计数低于2000/mm²的百分比从四十多岁供体的3.9%升至七十多岁供体的6%。对于40至69岁的供体，按照美国眼库协会现行标准，在另外3.3%经过预筛选的角膜库中，角膜内皮显微镜检查用于排除不可接受的组织。虽然该眼库最初认为69岁以上供体的角膜不可用于移植，但常规角膜内皮显微镜检查帮助该年龄组31名供体的角膜通过了移植评估。
