Litchfield W R, Dluhy R G
Endocrine-Hypertension Division, Brigham and Women's Hospital, Boston Massachusetts, USA.
Endocrinol Metab Clin North Am. 1995 Sep;24(3):593-612.
The mineralocorticoid-excess state caused by primary aldosteronism usually causes hypokalemia and moderate to sever hypotension. A directed approach to the patient with suspected primary aldosteronism is essential. Appropriate use of biochemical and diagnostic imaging studies can identify the etiology of the primary aldosteronism in an efficient and noninvasive way in most cases. Precision in defining the etiology of the mineralocorticoid-excess state logically leads to therapeutic strategies that usually cure or improve the hypertensive state.
原发性醛固酮增多症引起的盐皮质激素过多状态通常会导致低钾血症和中度至重度低血压。对于疑似原发性醛固酮增多症的患者，采取有针对性的方法至关重要。在大多数情况下，合理运用生化和诊断性影像学检查能够以高效且无创的方式确定原发性醛固酮增多症的病因。精准界定盐皮质激素过多状态的病因，从逻辑上讲会导向通常能治愈或改善高血压状态的治疗策略。
