Kong L, Zhang C, Chen M, Xue G
Department of Ophthalmology, First Teaching Hospital, Henan Medical University, Zhengzhou, China.
Yan Ke Xue Bao. 1995 Mar;11(1):53-6.
The authors accumulated 15 cases (26 eyes) of steroid glaucoma due to topical administration of dexamethasone or prednisolone.
From 1970 to 1990, 26 eyes in 15 cases were observed (bilateral 11 cases, unilateral 4 cases) including 12 right eyes and 14 left eyes. 10 cases were male and 5 cases female with age ranging from 14 to 52 years averaging 28 years. 25 eyes had the manifestation of chronic open angle glaucoma in the clinical course, and 1 eye simulated an acute glaucoma attack.
All patients had taken antiglaucoma medication before coming to our hospital, but the IOP was over 6.7 kPa in 9 eyes. The C/D ratio was equal to or over 0.6 in 9 cases (16 eyes), and the values were inconsistent between both eyes in 55% of the patients. Treatment for glaucoma was immediate discontinuation of the steroids with antiglaucoma medication if necessary. Three eyes received filtering operations and 2 eyes had the removal of subconjunctival residual steroid. Normal IOP was restored in months up to a year.
Dexamethasone or prednisolone were the easiest to induce steroid glaucoma when the patients had long-term use of steroid eyedrops.
作者积累了15例（26只眼）因局部应用地塞米松或泼尼松龙导致的类固醇性青光眼病例。
1970年至1990年，观察了15例中的26只眼（双侧11例，单侧4例），包括右眼12只，左眼14只。男性10例，女性5例，年龄14至52岁，平均28岁。25只眼在临床过程中表现为慢性开角型青光眼，1只眼模拟急性青光眼发作。
所有患者在来我院之前均已使用抗青光眼药物，但9只眼的眼压超过6.7kPa。9例（16只眼）的杯盘比等于或超过0.6，55%的患者双眼数值不一致。青光眼的治疗是立即停用类固醇药物，必要时使用抗青光眼药物。3只眼接受了滤过手术，2只眼清除了结膜下残留的类固醇。眼压在数月至一年内恢复正常。
当患者长期使用类固醇眼药水时，地塞米松或泼尼松龙最容易诱发类固醇性青光眼。
