Guha D, Sarkar N, Sarkar B
Department of Physiology, Calcutta University, University College of Science & Technology, India.
Indian J Exp Biol. 1995 Oct;33(10):788-90.
Effect of electrolytic lesion in vestibulo-cerebellar area of male Wistar rats was investigated on duodenal alkaline phosphatase (AP) activity. Histomorphological observations of brain indicated, that extensive lesion restricted to the wide area of nodule including ventral uvula, resulted in significant fall of AP activity at the mucosal brush border within 20 days. A comparative behavioural study in experimental and control groups by openfield test indicated that, sympathoexcitation resulting from vestibulo-cerebellar lesion may contribute to significant alteration of AP activity in duodenum of rats.
研究了电解损伤雄性Wistar大鼠前庭小脑区域对十二指肠碱性磷酸酶（AP）活性的影响。对大脑的组织形态学观察表明，广泛的损伤局限于包括腹侧蚓垂在内的小结广泛区域，导致20天内黏膜刷状缘的AP活性显著下降。通过旷场试验对实验组和对照组进行的比较行为研究表明，前庭小脑损伤引起的交感神经兴奋可能导致大鼠十二指肠AP活性的显著改变。
