[脉冲电磁场对大鼠心肌肌浆网钙离子蓄积的影响]
[Effects of an impulse electromagnetic field on calcium ion accumulation in the sarcoplasmic reticulum of the rat myocardium].
作者信息
Loginov V A, Gorbatenkova N V, Klimovitskiĭ V Ia
出版信息
Kosm Biol Aviakosm Med. 1991 Sep-Oct;25(5):51-3.
PMID:8577145
Abstract
By means of an ion-selective electrode, the effect of an impulse electromagnetic field with a 1 ms impulse, 10 Hz frequency, and 1-10 mT magnetic induction on calcium transport was investigated in the presence of potassium oxalate by rat heart homogenates. Prolonged exposure (100 min) to the field produced 70% inhibition of Ca2+ transfer across the sarcoplasmic reticulum. This effect is associated with direct inhibition of Ca(2+)-ATPase.
摘要
通过离子选择电极，在草酸钾存在的情况下，利用大鼠心脏匀浆研究了脉冲宽度为1毫秒、频率为10赫兹、磁感应强度为1 - 10毫特斯拉的脉冲电磁场对钙转运的影响。长时间（100分钟）暴露于该电磁场会使肌浆网跨膜Ca2+转运受到70%的抑制。这种效应与Ca(2+)-ATP酶的直接抑制有关。
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