Medvedev L G, Kuleshov V I, Shevchenko S B
Kosm Biol Aviakosm Med. 1991 Nov-Dec;25(6):27-30.
Biochemical changes in response to a high partial pressure of oxygen were investigated in 12 test subjects. During exposure to compressed oxygen breathing (pO2-0.25 MPa) for a limited period of time changes in the carbohydrate, protein, enzyme, and electrolyte status were seen. These changes were demonstrative sings of physiological and toxic effects of oxygen. Individual metabolic responses were investigated and optimal exposure times were determined. It is recommended to take into consideration biochemical variations when identifying human resistance to oxygen toxicity on an individual basis.
在12名受试对象中研究了对高氧分压的生化反应。在短时间暴露于压缩氧气呼吸（pO2 - 0.25 MPa）期间，观察到碳水化合物、蛋白质、酶和电解质状态的变化。这些变化是氧气生理和毒性作用的明显迹象。研究了个体代谢反应并确定了最佳暴露时间。建议在个体层面确定人体对氧中毒的耐受性时考虑生化变化。
