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[实验条件下小白鼠间皮细胞增殖的放射自显影研究]

[Autoradiographic study of mesothelial proliferation in white mice under experimental conditions].

作者信息

Ivanova V F, Puzyrev A A

出版信息

Arkh Anat Gistol Embriol. 1977 Feb;72(2):10-7.

PMID:857774
Abstract

The proliferative activity (mitotic cycle, proliferative pool) of the mesothelium of the parietal peritoneum of white mice acted upon by distilled water was studied autoradiographically with H3-thymidine. The mesothelium regenerated due to high mitotic activity and increased amount of polynuclear cells. The latter are formed as a result of amitotic and mitotic division of the nucleus without plasmotomy. The distribution of cells at the stage of DNA synthesis and mitosis in all the parietal peritoneum speaks of the absence of special proliferation zones.

摘要

用H3-胸腺嘧啶核苷通过放射自显影法研究了蒸馏水作用下小白鼠壁腹膜间皮的增殖活性(有丝分裂周期、增殖池)。由于有丝分裂活性高和多核细胞数量增加,间皮发生再生。后者是细胞核进行无胞质分裂的无丝分裂和有丝分裂的结果。壁腹膜所有部位处于DNA合成期和有丝分裂期的细胞分布表明不存在特殊的增殖区。

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