Kornblut A D, Westphal P, Miehlke A
Arch Otolaryngol. 1977 May;103(5):258-61. doi: 10.1001/archotol.1977.00780220052003.
The Frey syndrome, or gustatory sweating, is an accepted complication of parotid gland surgery that may occur with varying degrees of secerity. Since misdirection of auriculotemporal secretomotor nerve fibers has been found to play an important role in the development of the syndrome, a study was initiated to attempt mechanical interference with the regenerating fibers of the nerve. A superiorly based muscle flap from the sternocleidomastoid muscle was developed to cover the operative wound after either partial or complete parotidectomy. Results in 35 patients with such a muscle flap were compared with those in 35 control patients for the presence of absence of the Frey syndrome; the muscle flap was shown to be ineffective in preventing occurrence of gustatory sweating. Moreover, gustatory sweating to varying degrees was present in 34 patients with the muscle flap and in 33 control patients. Also, only 23 of the 70 patients had subjective complaints related to the syndrome, none of whom was incapacitated ore required additional measures for care.
弗雷综合征，即味觉性出汗，是腮腺手术公认的一种并发症，其严重程度可能各不相同。由于发现耳颞部分泌运动神经纤维的迷走再生在该综合征的发生中起重要作用，因此开展了一项研究，试图对该神经的再生纤维进行机械干预。在部分或全腮腺切除术后，制作一块以胸锁乳突肌为蒂的肌瓣来覆盖手术创口。将35例使用这种肌瓣的患者与35例对照患者的弗雷综合征发生情况进行了比较；结果显示该肌瓣在预防味觉性出汗的发生方面无效。此外，34例使用肌瓣的患者和33例对照患者均有不同程度的味觉性出汗。而且，70例患者中只有23例有与该综合征相关的主观症状，其中无一例失能或需要额外的护理措施。
