来自嗜酸热原体的长链二甘油四醚

Long-chain diglycerol tetraethers from Thermoplasma acidophilum.

作者信息

Langworthy T A

出版信息

Biochim Biophys Acta. 1977 Apr 26;487(1):37-50. doi: 10.1016/0005-2760(77)90042-x.

Abstract

The C40 isopranol-containing glycerol ether residues which characterize the complex lipids of the extreme thermoacidophile Thermoplasma acidophilum were isolated and purified from the glycolipid and phospholipid fractions. The glycerol ether, as well as the acetate and methoxy derivatives were characterized by thin-layer, gel-permeation and gas-liquid chromatography, infrared, nuclear magnetic resonance and mass spectrometry and by vapor phase osmometry. The glycerol ethers are proposed to be unique fully saturated diglycerol tetraethers, primarily C86H172O6, Mr 1300, which contain two sn-2,3-glycerol residues bridged through ether linkages by two C40 isopranoid branched diols.

摘要

从嗜热嗜酸栖热菌（Thermoplasma acidophilum）的复合脂质中分离并纯化出了具有特征性的含C40异戊醇的甘油醚残基，这些残基存在于糖脂和磷脂组分中。通过薄层色谱、凝胶渗透色谱和气液色谱、红外光谱、核磁共振光谱、质谱以及气相渗透压测定法对甘油醚以及乙酸酯和甲氧基衍生物进行了表征。甘油醚被认为是独特的全饱和二甘油四醚，主要为C86H172O6，分子量为1300，它含有两个通过醚键由两个C40类异戊二烯支链二醇桥连的sn-2,3-甘油残基。