Dale P S, Wardlaw J C, Wootton D G, Resnick J I, Giuliano A E
Joyce Eisenberg Keefer Breast Center, John Wayne Cancer Institute at Saint John's Hospital and Health Center, Santa Monica, CA 90404, USA.
Ann Plast Surg. 1995 Nov;35(5):515-8. doi: 10.1097/00000637-199511000-00012.
We present a case of desmoid tumor associated with prior alloplastic breast reconstruction. Wide local excision that includes chest wall resection, if necessary, is the primary treatment of choice. Patients with extensive nonresectable or recurrent disease may benefit from radiation therapy. Systemic therapy is a possibility in certain cases, but its toxicity generally precludes its use with this nonmetastatic tumor. Although this is the fourth reported case of desmoid tumor arising after implantation of a silicone prosthesis, we cannot claim a causal relationship. Careful follow-up consisting of yearly physical and mammagraphic examinations may facilitate early diagnosis and treatment of locally aggressive desmoid tumors but is not warranted, except in the context of routine screening for breast carcinoma.
我们报告一例与既往异体乳房重建相关的硬纤维瘤病例。必要时，包括胸壁切除的广泛局部切除是主要的治疗选择。患有广泛不可切除或复发性疾病的患者可能从放射治疗中获益。在某些情况下，全身治疗是一种选择，但其毒性通常使其不适用于这种非转移性肿瘤。尽管这是第四例报道的硅胶假体植入后发生硬纤维瘤的病例，但我们不能认定存在因果关系。除了在乳腺癌常规筛查的背景下，由每年的体格检查和乳腺钼靶检查组成的仔细随访可能有助于早期诊断和治疗局部侵袭性硬纤维瘤，但并无必要。
