Optimal control analysis in the chemotherapy of IgG multiple myeloma.

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作者信息

Swan G W, Vincent T L

出版信息

Bull Math Biol. 1977;39(3):317-37. doi: 10.1007/BF02462912.

DOI:10.1007/BF02462912

PMID:857983

Abstract

摘要

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Optimal control analysis in the chemotherapy of IgG multiple myeloma.

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State vector description of the proliferation of mammalian cells in tissue culture. I. Exponential growth.组织培养中哺乳动物细胞增殖的状态向量描述。I. 指数生长。

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Dose-response curves for agents that impair cell reproductive integrity. The relation between dose-response curves and the design of selective regimens in cancer chemotherapy.损害细胞生殖完整性的药物的剂量-反应曲线。癌症化疗中剂量-反应曲线与选择性治疗方案设计之间的关系。

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Improvement of the model systems.模型系统的改进。

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Pharmacodynamics of chemotherapeutic effects: dose-time-response relationships for phase-nonspecific agents.化疗效果的药效学：非特异性时相药物的剂量-时间-反应关系

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Kinetics of tumor growth and regression in IgG multiple myeloma.IgG 型多发性骨髓瘤中肿瘤生长与消退的动力学

J Clin Invest. 1972 Jul;51(7):1697-708. doi: 10.1172/JCI106971.

Some strategies for harvesting a single species.一些针对单一物种的捕捞策略。

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