Kass L
Department of Pathology, Case Western Reserve, University School of Medicine, Cleveland, Ohio, USA.
Biotech Histochem. 1995 Sep;70(5):271-4. doi: 10.3109/10520299509108206.
Megakaryocytes from normal persons and from patients with immune thrombocytopenic purpura, myelodysplastic disorders, hypersplenism, and essential thrombocythemia displayed vivid magenta metachromatic staining of the cytoplasm when stained with basic black MSP followed by brief exposure to dilute hydrochloric acid. Under the same conditions, other hematopoietic cells were completely decolorized. Acid fast metachromasia of megakaryocytes facilitates their identification, particularly in cases of small and atypical megakaryocytes found in disease states.
用碱性黑MSP染色后短暂暴露于稀盐酸中，正常人和免疫性血小板减少性紫癜、骨髓增生异常综合征、脾功能亢进及原发性血小板增多症患者的巨核细胞胞质呈现鲜艳的品红色异染性染色。在相同条件下，其他造血细胞则完全脱色。巨核细胞的耐酸异染性有助于其识别，尤其是在疾病状态下发现的小而不典型的巨核细胞病例中。
