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Clozapine does not elevate serum prolactin levels in healthy men.

作者信息

Lee H S, Kim C H, Song D H, Choi N K, Yoo K J

机构信息

Department of Psychiatry, Yonsei University, College of Medicine, Seoul, Korea.

出版信息

Biol Psychiatry. 1995 Dec 1;38(11):762-4. doi: 10.1016/0006-3223(95)00366-5.

DOI:10.1016/0006-3223(95)00366-5
PMID:8580231
Abstract
摘要

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Clozapine does not elevate serum prolactin levels in healthy men.氯氮平不会提高健康男性的血清催乳素水平。
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2
Comparison of clozapine and haloperidol on some autonomic and psychomotor functions, and on serum prolactin concentration, in healthy subjects.氯氮平与氟哌啶醇对健康受试者某些自主神经和精神运动功能以及血清催乳素浓度的比较。
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Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of clozapine, but not haloperidol.随后亚慢性给予氯氮平可改善苯环利定诱导的小鼠认知缺陷,但氟哌啶醇则无此作用。
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S18327 (1-[2-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)piperid-1-yl]ethyl]3-phenyl imidazolin-2-one), a novel, potential antipsychotic displaying marked antagonist properties at alpha(1)- and alpha(2)-adrenergic receptors: II. Functional profile and a multiparametric comparison with haloperidol, clozapine, and 11 other antipsychotic agents.S18327(1-[2-[4-(6-氟-1,2-苯并异恶唑-3-基)哌啶-1-基]乙基]-3-苯基咪唑啉-2-酮),一种新型潜在抗精神病药物,对α(1)和α(2)肾上腺素能受体显示出显著的拮抗特性:II. 功能特征以及与氟哌啶醇、氯氮平及其他11种抗精神病药物的多参数比较
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Acute and chronic administration of clozapine produces greater proconvulsant actions than haloperidol on focal hippocampal seizures in freely moving rats.
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S 16924 ((R)-2-[1-[2-(2,3-dihydro-benzo[1,4] dioxin-5-Yloxy)-ethyl]-pyrrolidin-3yl]-1-(4-fluoro-phenyl)-ethanone), a novel, potential antipsychotic with marked serotonin (5-HT)1A agonist properties: I. Receptorial and neurochemical profile in comparison with clozapine and haloperidol.S 16924((R)-2-[1-[2-(2,3-二氢-苯并[1,4]二氧杂环己烯-5-基氧基)-乙基]-吡咯烷-3-基]-1-(4-氟苯基)-乙酮),一种具有显著5-羟色胺(5-HT)1A激动剂特性的新型潜在抗精神病药物:I. 与氯氮平和氟哌啶醇相比的受体及神经化学特征
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Effect of chlorpromazine and clozapine on plasma concentrations of haloperidol in a patient with schizophrenia.氯丙嗪和氯氮平对一名精神分裂症患者血浆中氟哌啶醇浓度的影响。
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Clozapine, but not haloperidol, increases neuropeptide Y neuronal expression in the rat hypothalamus.氯氮平而非氟哌啶醇可增加大鼠下丘脑神经肽Y神经元的表达。
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Possible individual and gender differences in the small increases in plasma prolactin levels seen during clozapine treatment.
在氯氮平治疗期间观察到的血浆催乳素水平小幅升高可能存在个体差异和性别差异。
Eur Arch Psychiatry Clin Neurosci. 2004 Oct;254(5):318-25. doi: 10.1007/s00406-004-0505-2.
4
Single- and multiple-dose pharmacokinetics of ziprasidone under non-fasting conditions in healthy male volunteers.齐拉西酮在健康男性志愿者非空腹条件下的单剂量和多剂量药代动力学。
Br J Clin Pharmacol. 2000;49 Suppl 1(Suppl 1):5S-13S. doi: 10.1046/j.1365-2125.2000.00147.x.