Wada H, Okubo K, Hirata T, Hitomi S
Department of Thoracic Surgery, Kyoto University, Japan.
Lung Cancer. 1995 Oct;13(2):113-20. doi: 10.1016/0169-5002(95)00484-x.
Bronchoplasty and pulmonary angioplasty(PA-plasty) have been performed in recent years for lung cancer invading the bronchus and pulmonary artery. We evaluated the results and complications in patients who underwent such operations. There were 23 cases of bronchoplasty performed between 1988 and October 1993. Of these 23 cases, 9 underwent PA-plasty with bronchoplasty. There were 8 males and 1 female (mean 65.6 year-old). There were 8 patients with primary lung cancer(sq 5, ad 1, la 1, and sm 1) and 1 with metastatic lung tumor of colon cancer. One patient was in p-stage II, 6 in p-stage III, and 1 in p-stage IV. Seven patients underwent right upper lobectomy, 1 did the right upper and middle bilobectomy, and 1 did a left upper lobectomy. Bronchoplasty was performed using sleeve resection in 8 patients, and a wedge resection in 1 patient. PA-plasty was performed using sleeve resection and end to end anastomosis in 2 cases, and using side wall resection and plasty in 7 patients after clamp. Of 9 patients in whom both broncho- and PA-plasty were performed, there was one with the resected bronchial stump of cancer-positive. Total resection of the cancer was possible in the remaining 8 patients. Postoperative complications included 2 pneumonia, 2 empyema, and 1 each, acute cardiac failure, pulmonary thrombus, and chylothorax. The patients with empyema required re-operation using omentopexy or thoracoplasty. Long-term results showed that 2 patients died because of recurrence. Another patient died of respiratory failure. The remaining 6 patients were alive without any evidence of cancer. Pneumonectomy was avoided and the combination of PA-plasty and bronchoplasty was performed instead. However, the incidence of postoperative complications was high, indicating that utmost care must be exercised in the postoperative management of these patients.
近年来,对于侵犯支气管和肺动脉的肺癌患者,已开展了支气管成形术和肺血管成形术(PA成形术)。我们评估了接受此类手术患者的手术结果及并发症情况。1988年至1993年10月期间共进行了23例支气管成形术。在这23例患者中,9例同时接受了PA成形术和支气管成形术。其中男性8例,女性1例(平均年龄65.6岁)。原发性肺癌患者8例(鳞状细胞癌5例、腺癌1例、大细胞癌1例、小细胞癌1例),1例为结肠癌肺转移瘤患者。1例患者为p-II期,6例为p-III期,1例为p-IV期。7例患者接受了右上叶切除术,1例接受了右上叶和中叶双叶切除术,1例接受了左上叶切除术。8例患者采用袖状切除术进行支气管成形术,1例采用楔形切除术。2例患者采用袖状切除术和端端吻合术进行PA成形术,7例患者在阻断后采用侧壁切除术和成形术。在同时进行支气管成形术和PA成形术的9例患者中,1例切除的支气管残端癌呈阳性。其余8例患者实现了癌症的完全切除。术后并发症包括2例肺炎、2例脓胸,以及各1例急性心力衰竭、肺血栓和乳糜胸。脓胸患者需要采用网膜固定术或胸廓成形术进行再次手术。长期结果显示,2例患者因复发死亡。另1例患者死于呼吸衰竭。其余6例患者存活,无癌症迹象。避免了全肺切除术,取而代之的是进行PA成形术和支气管成形术联合手术。然而,术后并发症的发生率较高,这表明在这些患者的术后管理中必须格外小心。