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[钩端螺旋体病在墨西哥的意义。献血人群中钩端螺旋体抗体的检测]

[Significance of human leptospirosis in Mexico. Detection of Leptospira antibodies in a blood donor population].

作者信息

Gavaldón D G, Cisneros M A, Rojas N, Moles-Cervantes L P

机构信息

Universidad Autónoma Metropolitana-Xochimilco, Departamentos de Atención a la Salud y Producción Agrícola y Animal, Coyoacán, México D.F.

出版信息

Gac Med Mex. 1995 May-Jun;131(3):289-92.

PMID:8582567
Abstract

The presence of specific serum antibodies has been used as a diagnostic test for human leptospirosis. The presence of these antibodies in humans is indicative of an active natural infection. Its detection after exposure denotes the presence of immunity. Serum samples from 206 adult blood donors were analyzed with a microscopic agglutination assay against 7 serovars of Leptospira interrogans. A total of 7% were positive with the following serovar distribution; shermani 53%, canicola 33%, pyrogens 20%, pomona 13% and icterohaemorrhagiae 6%. The highest frequency of seropositivity was found in the 20 year to 39 age group. These results in asymptomatic individuals show that leptospirosis is a frequent zoonosis in Mexico.

摘要

特定血清抗体的存在已被用作人类钩端螺旋体病的诊断测试。人类体内这些抗体的存在表明存在活跃的自然感染。接触后检测到这些抗体表明存在免疫力。采用针对问号钩端螺旋体7个血清型的显微镜凝集试验,对206名成年献血者的血清样本进行了分析。共有7%的样本呈阳性,血清型分布如下:舍曼尼型53%、犬型33%、致热型20%、波摩那型13%和出血性黄疸型6%。血清阳性率最高的是20至39岁年龄组。这些无症状个体的检测结果表明,钩端螺旋体病在墨西哥是一种常见的人畜共患病。

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