Lalonde R J, Hunt J W
Hamilton Regional Cancer Centre, Ontario, Canada.
IEEE Trans Biomed Eng. 1995 Oct;42(10):981-90. doi: 10.1109/10.464372.
A method is described for generating ultrasound focus patterns for ultrasound hyperthermia treatment planning for steady state and transient hyperthermia. The solution for placement and intensity of ultrasound focus points is based on two types of temperature constraints: 1) equality constraints on the tumor boundary (temperature is held at maximum safe level) and 2) inequality constraints in the tumor interior (in a therapeutic range of temperatures). The method employs a simplex algorithm to solve a series of linear equations which approximate the heating distribution in tissue. Examples are given for field conjugate acoustic lens applicators capable of generating multiple foci simultaneously.
本文描述了一种用于生成超声聚焦模式的方法，该方法用于稳态和瞬态热疗的超声热疗治疗计划。超声焦点的放置和强度的解决方案基于两种类型的温度约束：1）肿瘤边界上的等式约束（温度保持在最大安全水平）和2）肿瘤内部的不等式约束（在治疗温度范围内）。该方法采用单纯形算法来求解一系列近似组织中热分布的线性方程。文中给出了能够同时产生多个焦点的场共轭声透镜 applicators 的示例。
