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兔输卵管和子宫不同部位对[U-C14-A1-葡萄糖]的体外摄取

Incorporation of [U-C14-A1-glucose in vitro by different parts of the rabbit Fallopian tube and uterus.

作者信息

Misra D, Roy S, Gupta D N, Karkun J N

出版信息

Endokrinologie. 1977 Feb;69(1):21-7.

PMID:858285
Abstract

The in vitro incorporation of E1U-C14]-glucose by ampullary and isthmic segments of the Fallopian tube and the uterus was determined in the intact (estrous), ovariectomized, ovariectomized plus estrogen and ovarietcomized plus estrogen + progesterone treated rabbit. In the intact animal the ampulla incorporated glucose at a faster rate than the isthmus; uterine uptake is minimal. Ovariectomy reduced the rate of incorporation below normal values in all the tissues. EDP (estradiol dipropionate) administered to ovariectomized rabbit increased the incorporation rate. Progesterone antagonized the EDP-induced uptake. The relative rate and pattern of incorporation by the three tissues were, however, determined by the dosage of estrogen and the estrogen/progesterone ratio.

摘要

在完整(发情期)、卵巢切除、卵巢切除加雌激素以及卵巢切除加雌激素+孕酮处理的兔子中,测定了输卵管壶腹部和峡部以及子宫对[E1U-C14]葡萄糖的体外摄取情况。在完整动物中,壶腹部摄取葡萄糖的速度比峡部快;子宫摄取量极少。卵巢切除使所有组织中的摄取率低于正常值。给卵巢切除的兔子注射二丙酸雌二醇(EDP)可提高摄取率。孕酮可拮抗EDP诱导的摄取。然而,这三种组织的相对摄取率和模式取决于雌激素剂量以及雌激素/孕酮比值。

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