Falco N A, Upton J
Division of Plastic Surgery, New England Deaconess Hospital, Harvard Medical School, Boston, MA, USA.
J Hand Surg Am. 1995 Nov;20(6):1014-20. doi: 10.1016/S0363-5023(05)80152-2.
A series of 15 digital lesions in 8 pediatric patients is presented. All infantile digital fibromas appear early in life at the distal or proximal interphalangeal joint level, characteristically involve the ulnar three digits, may be multicentric, and undergo rapid growth within a short time. Histology reveals deep dermal origin and intracytoplasmic inclusion bodies not observed in any other fibrous proliferative disorders. A viral etiology has never been proved. The lesions may recur despite wide excision followed by resurfacing with a flap or graft. This distinctive lesion has no adult counterpart and should be considered in the differential diagnosis of hard, immobile distal digital masses in children.
本文报告了8例儿科患者的15个手指病变。所有婴儿指纤维瘤均在生命早期出现在远端或近端指间关节水平，特征性地累及尺侧三个手指，可能为多中心性，并在短时间内迅速生长。组织学检查显示起源于真皮深层，且在任何其他纤维增生性疾病中均未观察到胞质内包涵体。病毒病因从未得到证实。尽管广泛切除并随后用皮瓣或移植物覆盖创面，病变仍可能复发。这种独特的病变在成人中没有对应物，在儿童坚硬、固定的远端手指肿块的鉴别诊断中应予以考虑。
