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游离空肠自体移植在咽食管段的功能

The function of free jejunal autografts in the pharyngo-oesophageal segment.

作者信息

Wilson J A, Maran A G, Pryde A, Walker W S, Heading R C

机构信息

Department of Otolaryngology Head and Neck Surgery, Royal Infirmary, Glasgow.

出版信息

J R Coll Surg Edinb. 1995 Dec;40(6):363-6.

PMID:8583435
Abstract

Eight patients were studied 6 weeks to 16 months following pharyngo-oesophageal reconstruction using a free jejunal interposition graft. Ambulatory manometry was carried out using an intraluminal strain gauge assembly linked to a portable microprocessor. In one patient, the assembly could not be passed because of a redundant jejunal loop. In four subjects, the jejunal interposition appeared to function as a passive conduit with very little manometric activity. In the remaining three patients, however, there was evidence of both propagated peristaltic waves within the graft and regular contractile activity, characteristic of Phase III of the intestinal Migrating Motor Complex (MMC). The presence of MMC activity at only 7 weeks following surgery confirms its independence of extrinsic intestinal innervation. Spontaneous contractile activity, however, was not interrupted by propagated water swallows and may contribute to post-operative dysphagia in some individuals.

摘要

对8例采用游离空肠移植进行咽食管重建的患者进行了6周~16个月的研究。使用与便携式微处理器相连的腔内应变片组件进行动态测压。1例患者因空肠袢冗长,组件无法通过。4例患者中,空肠移植似乎起到了被动管道的作用,测压活动极少。然而,在其余3例患者中,有证据表明移植物内存在传播性蠕动波以及规律性收缩活动,这是肠道移行性运动复合波(MMC)第三相的特征。术后仅7周就出现MMC活动,证实其不依赖于肠道外在神经支配。然而,传播性水吞咽并未中断自发收缩活动,这可能是导致部分患者术后吞咽困难的原因。

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