Hanson R P, Chow T K, Feehan E, Eadie P A, Timon C T, Keogh S
Plastic and Reconstructive Department, St James's Hospital, St James's Gate, Dublin 8, Ireland.
J Plast Reconstr Aesthet Surg. 2007;60(6):577-82. doi: 10.1016/j.bjps.2006.11.012. Epub 2007 Jan 24.
Surgical treatment of hypopharyngeal cancers with extension to the postcricoid region generally requires a circumferential pharyngolaryngoesphagectomy followed by reconstruction of the upper aerodigestive tract. Many techniques have been described in order to achieve a safe and functional reconstruction. Interposition of the jejunal free flap (JFF) is a well-established technique and is the flap of choice in our unit. This is a retrospective review of all patients who required a JFF following pharyngolaryngoesphagectomy over an 9-year period. We studied medical charts, histological reports, and speech and language therapy assessments. Eight of the nine surviving patients completed a quality of life questionnaire. Analysis was carried out on patient demographics, flap survival, patient survival and quality of life including swallow function and speech restoration. A total of 23 patients had 24 jejunal free flaps. There were four perioperative deaths. Two flaps failed, and were salvaged with a second JFF in one case and a gastric pull-up in the second. Functioning swallow was established in 74% of patients with four patients complaining of dysphagia. Speech was restored using an electrolarynx or Blom Singer valve in 70% of patients. Most patients required radiotherapy as part of their adjuvant treatment. In our hands the JFF for reconstruction following pharyngolaryngoesophageal resection allows restoration of function following major ablative surgery.
下咽癌侵犯至环状软骨后区的手术治疗通常需要进行环周性下咽-喉-食管切除术,随后重建上消化道。为实现安全且功能性的重建,已描述了多种技术。游离空肠瓣(JFF)移植是一种成熟的技术,也是我们科室的首选皮瓣。这是一项对9年间所有下咽-喉-食管切除术后需要JFF的患者的回顾性研究。我们研究了病历、组织学报告以及言语和语言治疗评估。9名存活患者中有8名完成了生活质量问卷。对患者的人口统计学特征、皮瓣存活情况、患者生存率以及包括吞咽功能和言语恢复在内的生活质量进行了分析。共有23例患者接受了24次游离空肠瓣移植。围手术期死亡4例。2例皮瓣失败,其中1例通过第二次游离空肠瓣移植挽救,另1例通过胃上提术挽救。74%的患者建立了有效的吞咽功能,4例患者主诉吞咽困难。70%的患者使用电子喉或Blom Singer瓣膜恢复了言语功能。大多数患者需要放疗作为辅助治疗的一部分。在我们手中,下咽-喉-食管切除术后使用游离空肠瓣重建可在大型切除术后恢复功能。