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一种新型前列腺素E1制剂治疗勃起功能障碍的长期疗效。

Long-term efficacy of a new formulation of prostaglandin E1 as treatment for erectile failure.

作者信息

Godschalk M, Gheorghiu D, Chen J, Katz P G, Mulligan T

机构信息

Division of Geriatrics Medicine, Medical College of Virginia, McGuire Veterans Affairs Medical Center, Richmond, USA.

出版信息

J Urol. 1996 Mar;155(3):915-7.

PMID:8583606
Abstract

PURPOSE

We determined the long-term efficacy of intracavernous injection of a new formulation of prostaglandin E1 (Caverject) as treatment for erectile failure.

MATERIALS AND METHODS

A prospective study was done at a university affiliated Veterans Affairs medical center. Subjects with erectile failure received injections of prostaglandin E1 at the office and self-administered injections at home for up to 18 months.

RESULTS

Of 16 patients who performed home injections 15 completed 6 months and 10 completed 18 months of therapy. Patient and spousal satisfaction with intercourse was 90% for months 1 to 6, and patient satisfaction was 95% for months 7 to 18.

CONCLUSIONS

Prostaglandin E1 was highly effective at producing penile rigidity and an erection with satisfactory vaginal intercourse.

摘要

目的

我们确定了海绵体内注射一种新配方的前列腺素E1(凯威捷)治疗勃起功能障碍的长期疗效。

材料与方法

在一所大学附属退伍军人事务医疗中心进行了一项前瞻性研究。勃起功能障碍患者在诊所接受前列腺素E1注射,并在家自行注射,为期长达18个月。

结果

16例进行家庭注射的患者中,15例完成了6个月的治疗,10例完成了18个月的治疗。第1至6个月患者及其配偶对性交的满意度为90%,第7至18个月患者满意度为95%。

结论

前列腺素E1在产生阴茎硬度及实现满意的阴道性交勃起方面非常有效。

相似文献

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Long-term efficacy of a new formulation of prostaglandin E1 as treatment for erectile failure.一种新型前列腺素E1制剂治疗勃起功能障碍的长期疗效。
J Urol. 1996 Mar;155(3):915-7.
2
Nocturnal penile tumescence activity unchanged after long-term intracavernous injection therapy.长期海绵体内注射治疗后夜间阴茎勃起活动无变化。
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Quality of life in patients using self-administered intracavernous injections of prostaglandin E1 for erectile dysfunction.
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[Prostaglandin treatment in neurological patients with erectile dysfunction].[前列腺素治疗神经功能障碍性勃起功能障碍患者]
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Pharmacokinetics of prostaglandin E1 and its main metabolites after intracavernous injection and short-term infusion of prostaglandin E1 in patients with erectile dysfunction.
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The long-term safety of alprostadil (prostaglandin-E1) in patients with erectile dysfunction. The European Alprostadil Study Group.前列地尔(前列腺素-E1)治疗勃起功能障碍患者的长期安全性。欧洲前列地尔研究小组。
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Long-term intracavernous therapy responders can potentially switch to sildenafil citrate after radical prostatectomy.长期接受海绵体内治疗有反应者在前列腺癌根治术后有可能改用枸橼酸西地那非。
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Comparison of satisfaction rates and erectile function in patients treated with sildenafil, intracavernous prostaglandin E1 and penile implant surgery for erectile dysfunction in urology practice.西地那非、海绵体内注射前列腺素E1及阴茎植入手术治疗泌尿外科勃起功能障碍患者的满意度及勃起功能比较
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引用本文的文献

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A risk-benefit assessment of sildenafil in the treatment of erectile dysfunction.西地那非治疗勃起功能障碍的风险效益评估。
Drug Saf. 2001;24(4):255-65. doi: 10.2165/00002018-200124040-00003.
2
Comparative tolerability and efficacy of treatments for impotence.阳痿治疗方法的耐受性和疗效比较
Drug Saf. 1999 Feb;20(2):133-46. doi: 10.2165/00002018-199920020-00004.
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Health-related quality of life in men with erectile dysfunction.勃起功能障碍男性的健康相关生活质量
J Gen Intern Med. 1998 Mar;13(3):159-66. doi: 10.1046/j.1525-1497.1998.00050.x.