应用脑胆碱酯酶复活来区分野生鸟类有机磷和氨基甲酸酯类农药暴露情况。

Application of brain cholinesterase reactivation to differentiate between organophosphorus and carbamate pesticide exposure in wild birds.

作者信息

Smith M R, Thomas N J, Hulse C

机构信息

National Biological Service, National Wildlife Health Center, Madison, Wisconsin 53711, USA.

出版信息

J Wildl Dis. 1995 Apr;31(2):263-7. doi: 10.7589/0090-3558-31.2.263.

DOI:10.7589/0090-3558-31.2.263

PMID:8583650

Abstract

Brain cholinesterase activity was measured to evaluate pesticide exposure in wild birds. Thermal reactivation of brain cholinesterase was used to differentiate between carbamate and organophosphorus pesticide exposure. Brain cholinesterase activity was compared with gas chromatography and mass spectrometry of stomach contents. Pesticides were identified and confirmed in 86 of 102 incidents of mortality from 29 states within the USA from 1986 through 1991. Thermal reactivation of cholinesterase activity was used to correctly predict carbamates in 22 incidents and organophosphates in 59 incidents. Agreement (P < 0.001) between predictions based on cholinesterase activities and GC/MS results was significant.

摘要

测量脑胆碱酯酶活性以评估野生鸟类接触农药的情况。利用脑胆碱酯酶的热激活作用来区分氨基甲酸酯类和有机磷农药接触情况。将脑胆碱酯酶活性与胃内容物的气相色谱和质谱分析结果进行比较。在美国，从1986年到1991年，在来自29个州的102起死亡事件中，有86起检测并确认了农药。胆碱酯酶活性的热激活作用被用于正确预测22起事件中的氨基甲酸酯类农药和59起事件中的有机磷农药。基于胆碱酯酶活性的预测与气相色谱/质谱分析结果之间的一致性（P < 0.001）非常显著。