Kishimoto N, Kato J, Suzuki T, Arakawa H, Ogawa S, Suzuki H
Department of Anesthesiology and Resuscitology, Kochi Medical School, Nankoku.
Masui. 1995 Dec;44(12):1680-4.
A 74 year-old woman with a 6-month history of RSD following herpes zoster on her right arm was treated with stellate ganglion blocks (SGB), continuous epidural block (CEB) and continuous intravenous infusion of ketamine known as one of the NMDA receptor blockers. Of the symptoms of RSD, burning pain and hyperperspiration but allodynia disappeared after the treatment with SGB 8 times and CEB for 4 days. Allodynia disappeared completely after ketamine treatment, where ketamine was infused once using a subanesthetic dose for 2 hours. It is considered that ketamine is one of the useful drugs for the treatment of neuropathic pain with allodynia.
一名74岁女性，右臂带状疱疹后出现6个月的反射性交感神经营养不良（RSD），接受了星状神经节阻滞（SGB）、持续硬膜外阻滞（CEB）以及作为N-甲基-D-天冬氨酸（NMDA）受体阻滞剂之一的氯胺酮持续静脉输注治疗。在RSD的症状中，灼痛和多汗症在进行8次SGB治疗和4天CEB治疗后消失，但痛觉过敏仍存在。在使用亚麻醉剂量的氯胺酮单次输注2小时后，痛觉过敏完全消失。氯胺酮被认为是治疗伴有痛觉过敏的神经性疼痛的有效药物之一。
