Kambara N, Kitamura S, Taniguchi A, Hamao W, Matsuyama M
Department of Anesthesiology, Osaka Children's Medical Center.
Masui. 1995 Dec;44(12):1707-11.
Seventy-seven children for minor surgery of less than 90 minutes in duration were divided into two groups; one group received midazolam syrup and the other received bromazepam suppository. The sedative effect before or after the induction of the anesthetic, the effect on the circulatory system, and the prolongation of the sedative effect after surgery were studied. Regarding the sedative effect before or during the induction of anesthesia, both medications were effective with no significant difference between the two groups. However, the bromazepam suppository had a significantly better sedative effect 1 or 2 hours after the surgery. In children under 4 years of age, the sedative effect during the induction was obtained by administering midazolam syrup before the surgery. It is indicated that midazolam syrup is superior to the bromazepam suppository in children under 4 years of age.
77名接受持续时间少于90分钟小手术的儿童被分为两组；一组接受咪达唑仑糖浆，另一组接受溴西泮栓剂。研究了麻醉诱导前或后的镇静效果、对循环系统的影响以及术后镇静效果的延长情况。关于麻醉诱导前或期间的镇静效果，两种药物均有效，两组之间无显著差异。然而，溴西泮栓剂在术后1或2小时具有明显更好的镇静效果。在4岁以下儿童中，通过术前给予咪达唑仑糖浆获得诱导期间的镇静效果。表明咪达唑仑糖浆在4岁以下儿童中优于溴西泮栓剂。
