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[双侧胸廓成形术后肺结核后遗症患者气道阻塞及其病因的长期研究]

[Long-term study of patients with pulmonary tuberculosis sequelae after bilateral thoracoplasty-airway obstruction and its causes].

作者信息

Zhou C, Nagayama N, Ohtsuka Y, Machida K, Mori M, Katayama T

机构信息

Department of Internal Medicine, Tokyo National Chest Hospital, Japan.

出版信息

Nihon Kyobu Shikkan Gakkai Zasshi. 1995 Nov;33(11):1180-5.

PMID:8583707
Abstract

Chest roentgenograms and results of pulmonary-function tests in patients with pulmonary tuberculosis sequelae 30 years after bilateral thoracoplasty were studied retrospectively to detect airway obstruction in these patients and to determine its causes. For periods of more than 10 years, vital capacity (VC) changed at a rate of 15.5 +/- 5.0 ml/year, and forced expiratory volume in one second as a percent of VC (FEV1%) changed at a rate of 0.546% +/- 0.380% per year (n = 13). Thirty years after thoracoplasty, the VC was 920 +/- 180 ml (%VC = 28.4% +/- 5.3%), and the FEV1% was 66.2% +/- 13.7% (n = 21). Thus, mild airway obstruction was found in about half of the cases. For each patient, the distance from the hilum to the diaphragm was measured along the mid-clavicular line on the side with fewer ribs resected, and this distance was divided by the patient's height. The results of that computation was found to be significantly and negatively related to FEV1% (r = -0.681, which suggests that longer bronchi in the lower and middle lobes on that side were associated with lower values of FEV1%. These findings are similar to those in patients with pulmonary tuberculous sequelae after total pneumonectomy. Over an average of 26 years, scoliosis, the vertebra showing the most bending, the intrapulmonary lesion, and the position of the diaphragm did not change, but the cardio-thoracic ratio increased.

摘要

对双侧胸廓成形术后30年的肺结核后遗症患者的胸部X线片和肺功能测试结果进行回顾性研究,以检测这些患者的气道阻塞情况并确定其原因。在超过10年的时间里,肺活量(VC)以每年15.5±5.0 ml的速度变化,一秒用力呼气量占VC的百分比(FEV1%)以每年0.546%±0.380%的速度变化(n = 13)。胸廓成形术后30年,VC为920±180 ml(%VC = 28.4%±5.3%),FEV1%为66.2%±13.7%(n = 21)。因此,约一半的病例存在轻度气道阻塞。对每位患者,沿着切除肋骨较少一侧的锁骨中线测量从肺门到膈肌的距离,并将该距离除以患者的身高。发现该计算结果与FEV1%显著负相关(r = -0.681),这表明该侧下叶和中叶较长的支气管与较低的FEV1%值相关。这些发现与全肺切除术后肺结核后遗症患者的发现相似。在平均26年的时间里,脊柱侧弯、弯曲最明显的椎体、肺内病变和膈肌位置没有变化,但心胸比率增加。

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