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[Ocular tuberculosis in systemic lupus erythematosus and immunosuppressive therapy].

作者信息

Anders N, Wollensak G

机构信息

Augenklinik im Virchow-Klinikum, Medizinische Fakultät der Humboldt-Universität zu Berlin.

出版信息

Klin Monbl Augenheilkd. 1995 Dec;207(6):368-71. doi: 10.1055/s-2008-1035391.

DOI:10.1055/s-2008-1035391
PMID:8583748
Abstract

BACKGROUND

A marked reduction in eye disease attributed to tuberculosis has occurred over the past several decades. In recent years, however, tuberculosis has reemerged as a serious public health problem. We report a case of a severe ocular tuberculosis in a patient with systemic lupus erythematosus and immunosuppressive therapy.

PATIENT

The 36-years-old woman underwent an immunosuppressive therapy because of a systemic lupus erythematosus detected two years earlier. After holidays on the Philippines Mycobacterium tuberculosis was found in a bronchial lavage. Two months later fundoscopy showed severe subretinal exsudation with overlying serous retinal detachment. Within several months these findings progressed to a panuveitis with spontaneous perforation. Histopathologically a granulomatous panophthalmitis could be found with giant cells. Two months later acid-fast bacilli were detected in orbital lesions.

CONCLUSION

In immunosuppressed patients there is still an increased risk for severe ocular tuberculosis. Therefore it is important to think of this almost forgotten disease in those cases.

摘要

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