Morvan D, Leroy-Willig A
Department of Biophysics, University Paris V-CoCHIN, France.
Magn Reson Imaging. 1995;13(7):943-8. doi: 10.1016/0730-725x(95)02006-f.
The aim of this study was to compare proton T2 and apparent diffusion coefficient (ADC) variations induced by exercise in skeletal muscle, to provide some more information on the source of their variations. T2 and ADC were measured in the forearm flexor digitorum muscles in 12 healthy volunteers at rest and after an exercise, using a sequence allowing simultaneous measurements of both parameters. At rest, T2 was 30.6 +/- 1.8 ms (mean +/- 1 SD) and ADC was 1.82 +/- 0.11 x 10(-9) m2/s. With exercise, T2 varied by +2.8 +/- 12% (p < .001 vs. rest) and ADC varied by +12 +/- 3% (p < .001). The recovery of T2 after exercise was faster than that of ADC, with half-times of 7 +/- 2 min and of 15 +/- 8 min (p < .01), respectively. It is concluded that both T2 and ADC with exercise are probably different, T2 mostly reflecting changes in water content and ADC reflecting temperature variations.
本研究的目的是比较运动引起的骨骼肌质子T2和表观扩散系数（ADC）的变化，以提供有关其变化来源的更多信息。在12名健康志愿者休息时和运动后，使用允许同时测量这两个参数的序列，测量其前臂屈指肌的T2和ADC。休息时，T2为30.6±1.8毫秒（平均值±1标准差），ADC为1.82±0.11×10⁻⁹平方米/秒。运动后，T2变化了+2.8±12%（与休息时相比，p<0.001），ADC变化了+12±3%（p<0.001）。运动后T2的恢复比ADC快，半衰期分别为7±2分钟和15±8分钟（p<0.01）。结论是，运动时T2和ADC可能都有所不同，T2主要反映水分含量的变化，而ADC反映温度变化。
