Schulz R, Ebner A, Schüller M, Pannek H, Holthausen H, Tuxhorn I, Noachtar S, Hoppe M, Oppel F, Wolf P
Epilepsiezentrum Bethel, Mara gGmbH, Bielefeld.
Nervenarzt. 1995 Dec;66(12):901-6.
Sixty-five patients (aged between 3 years 5 months and 60 years) suffering from medically resistant temporal lobe epilepsy (TLE) were operated on over a period of 33 months in Bethel Epilepsy Center. Thirty-three patients had mesial TLE and 32 patients had TLE of different etiology. The postoperative follow-up lasted 2 years in 30 patients and was on average 13.2 months or at least 8 months in the 35 patients who did not have their last examination 2 years after surgery. Many of the patients (70.9%) were seizure-free; 92.3% achieved a rewarding improvement in seizure frequency and quality of life. Reduction of medication was the cause for relapse in 10 patients, in 6 patients incomplete resection, and in 5 patients the prognosis was not good even before surgery. The cause remained unclear in 4 patients. Freedom from seizures was achieved again by renewed medication or by repeated operation in 10 of 25 patients.
在伯特利癫痫中心，65名患有药物难治性颞叶癫痫（TLE）的患者（年龄在3岁5个月至60岁之间）在33个月的时间里接受了手术。33例为内侧颞叶癫痫，32例为不同病因的颞叶癫痫。30例患者术后随访2年，35例未在术后2年进行最后一次检查的患者平均随访13.2个月或至少8个月。许多患者（70.9%）无癫痫发作；92.3%的患者癫痫发作频率和生活质量得到了有益改善。10例患者因减少用药而复发，6例因切除不完全复发，5例患者甚至在手术前预后就不佳。4例患者的复发原因不明。25例患者中有10例通过重新用药或再次手术再次实现无癫痫发作。
