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QSAR of N2-phenylguanidines as inhibitors of herpes simplex virus-1 thymidine kinase.

作者信息

Hadjipavlou-Litina D

机构信息

Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, Greece.

出版信息

Pharmazie. 1995 Dec;50(12):796-8.

PMID:8584555
Abstract

Quantitative structure-activity relationships were developed to account for inhibition of Herpes simplex virus type 1 by N2-phenylguanines. It was found that the hydrophobic and especially the steric properties of the substituents determine the relative potencies of the derivatives.

摘要

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