Hadjipavlou-Litina D
Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, Greece.
Pharmazie. 1995 Dec;50(12):796-8.
Quantitative structure-activity relationships were developed to account for inhibition of Herpes simplex virus type 1 by N2-phenylguanines. It was found that the hydrophobic and especially the steric properties of the substituents determine the relative potencies of the derivatives.