Yetkin F Z, Papke R A, Mark L P, Daniels D L, Mueller W M, Haughton V M
Department of Radiology, Medical College of Wisconsin, Milwaukee 53226, USA.
AJNR Am J Neuroradiol. 1995 Nov-Dec;16(10):2109-13.
To determine the value of functional MR imaging to supplement conventional MR imaging for locating the rolandic cortex.
Parasagittal MR images acquired in conjunction with functional MR images were reviewed. The central sulcus was identified on the MR images by conventional parcellation methods. In the functional MR images, the sensorimotor cortex (rolandic cortex) was identified by the activation secondary to finger and thumb movement or tactile stimulation of the palm. The location of the central sulcus and rolandic cortex was compared.
In 18 of 23 studies, the central sulcus selected by anatomic criteria coincided exactly or approximately with the cortex activated by the motor or sensory tasks. In two cases of tumor, the rolandic cortex could be located by means of the activation, but the central sulcus was not identified because of severe distortion of anatomic landmarks. In two volunteers, the central sulcus identified by anatomic landmarks did not coincide with the activated cortex.
This study demonstrates that functional imaging supplements anatomic imaging in locating the sensorimotor cortex. Functional MR imaging may be a useful adjunct to conventional MR imaging to determine noninvasively the proximity of eloquent brain to focal brain lesions.
确定功能磁共振成像（fMRI）辅助传统磁共振成像（MRI）定位中央前回皮质的价值。
回顾与功能磁共振图像联合采集的矢状旁位磁共振图像。通过传统的脑区划分方法在磁共振图像上识别中央沟。在功能磁共振图像中，通过手指和拇指运动或手掌触觉刺激继发的激活来识别感觉运动皮质（中央前回皮质）。比较中央沟和中央前回皮质的位置。
在23项研究中的18项中，根据解剖学标准选择的中央沟与运动或感觉任务激活的皮质完全或大致重合。在2例肿瘤病例中，可通过激活定位中央前回皮质，但由于解剖标志严重变形，未识别出中央沟。在2名志愿者中，通过解剖标志识别的中央沟与激活的皮质不重合。
本研究表明，功能成像在定位感觉运动皮质方面补充了解剖成像。功能磁共振成像可能是传统磁共振成像的有用辅助手段，用于无创确定明确脑区与局灶性脑病变的接近程度。
