Sitges-Serra A, Pi-Suñer T, Garces J M, Segura M
Department of Surgery, Hospital Universitari del Mar, Barcelona, Spain.
Am J Infect Control. 1995 Oct;23(5):310-6. doi: 10.1016/0196-6553(95)90062-4.
Intravascular catheters are contaminated by bacterial flora present on the patient's own skin or on the hands of the personnel manipulating the catheter-tubing junction. In the former case, contamination is more often extraluminal and often leads to CRS soon after catheter insertion. In the second circumstance, contamination preferentially involves the endoluminal route and results in bacteremia after the initial 10 to 14 days of catheter use. Effective prevention relies on thorough aseptic technique during insertion of the catheter or manipulation of its hub. Further studies are required to define the best means of achieving permanent sterilization of the insertion site. New hub designs should reduce the risk of hub contamination and CRS in prolonged intravascular catheterizations.
血管内导管会被患者自身皮肤上或操作导管- tubing 连接处的人员手上存在的细菌菌群污染。在前一种情况下，污染更多是管腔外的，并且在导管插入后不久常导致CRS。在第二种情况下，污染优先涉及管腔内途径，并在导管使用最初的10至14天后导致菌血症。有效的预防依赖于导管插入或其接头操作期间的彻底无菌技术。需要进一步研究来确定实现插入部位永久灭菌的最佳方法。新的接头设计应降低长期血管内插管时接头污染和CRS的风险。
