通过凝胶电泳检测双链DNA中的错配碱基。 - Suppr

Detection of mismatched bases in double stranded DNA by gel electrophoresis.

作者信息

Ganguly A, Prockop D J

机构信息

Department of Biochemistry and Molecular Biology, Jefferson Institute of Molecular Medicine, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA 19107, USA.

出版信息

Electrophoresis. 1995 Oct;16(10):1830-5. doi: 10.1002/elps.11501601301.

DOI:10.1002/elps.11501601301

PMID:8586050

Abstract

摘要

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Detection of mismatched bases in double stranded DNA by gel electrophoresis.通过凝胶电泳检测双链DNA中的错配碱基。

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Conformation-sensitive gel electrophoresis.构象敏感性凝胶电泳

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Magnetic bead-isolated single-strand DNA for SSCP analysis.

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Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: evidence for solvent-induced bends in DNA heteroduplexes.用于快速检测双链PCR产物和DNA片段中单碱基差异的构象敏感性凝胶电泳：DNA异源双链体中溶剂诱导弯曲的证据

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Analysis of population structures of viral isolates using single-strand conformation polymorphism method.采用单链构象多态性方法分析病毒分离株的群体结构。

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Conformation-sensitive gel electrophoresis.构象敏感凝胶电泳

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Phylogenetic network of the mtDNA haplogroup U in Northern Finland based on sequence analysis of the complete coding region by conformation-sensitive gel electrophoresis.基于构象敏感凝胶电泳对完整编码区的序列分析，芬兰北部线粒体DNA单倍群U的系统发育网络。

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Conformation sensitive gel electrophoresis for simple and accurate detection of mutations: comparison with denaturing gradient gel electrophoresis and nucleotide sequencing.用于简单准确检测突变的构象敏感凝胶电泳：与变性梯度凝胶电泳和核苷酸测序的比较

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Analysis of the COL1A1 and COL1A2 genes by PCR amplification and scanning by conformation-sensitive gel electrophoresis identifies only COL1A1 mutations in 15 patients with osteogenesis imperfecta type I: identification of common sequences of null-allele mutations.通过聚合酶链反应（PCR）扩增及构象敏感性凝胶电泳扫描对COL1A1和COL1A2基因进行分析，结果显示在15例Ⅰ型成骨不全患者中仅发现COL1A1基因突变：无义等位基因突变常见序列的鉴定。

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Detection of mismatched bases in double stranded DNA by gel electrophoresis.

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