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正常人体内静脉注射地高辛后直接血管效应和变力效应的时间顺序。

Time sequence of direct vascular and inotropic effects following intravenous administration of digoxin in normal man.

作者信息

Schinz A, Schnelle K, Klein G, Blömer H

出版信息

Int J Clin Pharmacol Biopharm. 1977 Apr;15(4):189-93.

PMID:858650
Abstract

The effects of a bolus injection of digoxin upon hemodynamics and left ventricular function were studied in 5 normal volunteers using cardiac ultrasound, ECG, carotid pulse pressure, and arterial blood pressure recording. Whereas the injection was followed by an immediate rise of the systemic vascular resistance, the inotropic action upon the myocardium followed with a delay of 10 to 30 minutes after injection.

摘要

利用心脏超声、心电图、颈动脉脉压及动脉血压记录,对5名正常志愿者研究了静脉注射地高辛对血流动力学和左心室功能的影响。注射后,全身血管阻力立即升高,而对心肌的正性肌力作用在注射后10至30分钟出现延迟。

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Time sequence of direct vascular and inotropic effects following intravenous administration of digoxin in normal man.正常人体内静脉注射地高辛后直接血管效应和变力效应的时间顺序。
Int J Clin Pharmacol Biopharm. 1977 Apr;15(4):189-93.
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