Inazumi T, Tajima S, Ando T, Shimada M
Department of Dermatology, Keio University School of Medicine, Tokyo, Japan.
J Dermatol. 1995 Oct;22(10):801-3. doi: 10.1111/j.1346-8138.1995.tb03925.x.
Cardiac manifestations of the CREST syndrome or limited systemic sclerosis (ISSc) are very rare. We report a case of CREST syndrome associated with sick sinus syndrome. Histopathology of cardiac muscle revealed fibrotic changes, suggesting that such changes may be pathogenetically related to CREST syndrome.
CREST综合征或局限性系统性硬化症（ISSc）的心脏表现非常罕见。我们报告一例与病态窦房结综合征相关的CREST综合征病例。心肌组织病理学显示有纤维化改变，提示这些改变可能在发病机制上与CREST综合征相关。
