Speller A M, Moffat D B
J Anat. 1977 Apr;123(Pt 2):487-500.
The postnatal development of the tubulo-vascular relationships in the kidney was studied in 60 rats. The kidney is relatively immature at birth and only the juxtamedullary glomeruli are present. As their loops of Henle develop they grow down into the medulla around the previously developed collecting ducts, forming tubulovascular 'units' around whose periphery the shorter loops of the more peripheral glomeruli grow down. The bundles of vasa recta develop in loose interstitial tissue which lies between the tubulo-vascular units so that the peripheral vessels of the bundles, which are ascending vasa recta, lie in close relationship with the descending short loops of Henle. Thus, the vascular bundles do not form the central axis around which the medullary components develop but rather take up the available space left after the tubulo-vascular units have developed. Development is virtually complete by the fourth week of postnatal life.
对60只大鼠的肾脏中肾小管 - 血管关系的产后发育进行了研究。出生时肾脏相对不成熟，仅存在近髓肾小球。随着它们的亨氏袢发育，它们向下生长到髓质中，围绕先前发育的集合管，形成肾小管 - 血管“单位”，更外周肾小球的较短袢在其周围向下生长。直小血管束在位于肾小管 - 血管单位之间的疏松间质组织中发育，因此束的外周血管（即直小血管升支）与亨氏袢的降支短袢密切相关。因此，血管束不是髓质成分围绕其发育的中心轴，而是占据肾小管 - 血管单位发育后留下的可用空间。产后第四周发育基本完成。
