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甲状腺功能亢进症中的线粒体转运核糖核酸

Mitochondrial tRNA in hyperthyroidism.

作者信息

Pasternak K, Szymonik-Lesiuk S, Brzuszkiewicz-Zarnowska H, Borkowski T

机构信息

Department of Physiological Chemistry, Medical Academy, Lublin, Poland.

出版信息

Acta Biochim Pol. 1995;42(2):227-31.

PMID:8588469
Abstract

The mitochondrial tRNA were prepared from liver and brain tissues of thyroxinized and control rabbits. The presence of tRNA for twenty amino acids both in liver and brain mitochondria was revealed. The quantity of radioactive amino acids bound to the mitochondrial tRNA was higher in hyperthyreosis than in control animals but considerable differences between the brain and liver tissues were observed.

摘要

从甲状腺素处理的兔子和对照兔子的肝脏及脑组织中制备线粒体tRNA。结果显示,肝脏和脑线粒体中均存在用于20种氨基酸的tRNA。与线粒体tRNA结合的放射性氨基酸数量在甲状腺功能亢进的兔子中高于对照动物,但在脑和肝组织之间观察到了显著差异。

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