Héron D, Lyonnet S, Iserin L, Munnich A, Padovani J P
Département de Pédiatrie, Hôpital des Enfants Malades, Paris, France.
Am J Med Genet. 1995 Nov 6;59(2):154-6. doi: 10.1002/ajmg.1320590207.
Cleft sternum is a rare malformation due to partial or total failure of sternal fusion at an early stage of embryonic development. Sternal clefts can be classified as superior, inferior, or complete. Here we report on a 2-year-old boy with inferior sternal cleft and complex cardiac malformation. We review a series of 9 children with sternal clefts, referred to us over a 10-year period. Hypothetical mechanisms for this developmental anomaly are discussed.
胸骨裂是一种罕见的畸形，由于胚胎发育早期胸骨融合部分或完全失败所致。胸骨裂可分为上型、下型或完全型。本文报告一名患有下型胸骨裂及复杂心脏畸形的2岁男孩。我们回顾了10年间转诊至我院的9例胸骨裂患儿病例。文中讨论了这种发育异常的可能机制。
