Pereira Arias J G, Astobieta Odriozola A, Prieto Ugidos N, Aurtenetxe Goiriena J J, Bernuy Malfaz C
Servicio de Urología, Hospital de Galdacano, Galdacano, Vizcaya, España.
Arch Esp Urol. 1995 Dec;48(10):1042-5.
Prostatic cancer can produce signs and symptoms by local growth, direct invasion or distant metastases. In rare occasions, these tumors can show a clinical variance due to trophic factors, biologically active, secreted in neoplastic environment but with systemic relevance. These syndromes are called paraneoplastic syndromes. This uncommon condition is described herein.
METHOD/RESULTS: We report a case of inappropriate antidiuretic hormone secretion as the presenting feature of advanced prostatic carcinoma. The pathogenic features, diagnostic and therapeutic aspects are reviewed.
Although its frequency is low, we must consider prostatic carcinoma in patients with inappropriate antidiuretic hormone secretion syndrome. When the acute situation is resolved, hormonal treatment in disseminated carcinomas will return to normal the clinical and analytical parameters derived from this syndrome.
前列腺癌可通过局部生长、直接侵犯或远处转移产生体征和症状。在极少数情况下，由于肿瘤环境中分泌的具有生物活性且具有全身相关性的营养因子，这些肿瘤可表现出临床变异。这些综合征被称为副肿瘤综合征。本文描述了这种罕见情况。
方法/结果：我们报告一例以抗利尿激素分泌异常为晚期前列腺癌首发特征的病例。对其致病特征、诊断和治疗方面进行了综述。
尽管其发生率较低，但对于抗利尿激素分泌异常综合征患者，我们必须考虑前列腺癌。当急性情况得到解决时，播散性癌的激素治疗将使源于该综合征的临床和分析参数恢复正常。
