胶原酶的帮手：类血红素结合蛋白结构域

A helping hand for collagenases: the haemopexin-like domain.

作者信息

Bode W

机构信息

Max-Planck-Institut für Biochemie, Planegg-Martinsried, Germany.

出版信息

Structure. 1995 Jun 15;3(6):527-30. doi: 10.1016/s0969-2126(01)00185-x.

DOI:10.1016/s0969-2126(01)00185-x

PMID:8590012

Abstract

The structures of the C-terminal domains of rabbit haemopexin and full-length porcine fibroblast collagenase reveal a common beta-propeller fold with pseudo-fourfold symmetry. The interactions of these haemopexin-like domains with target proteins and ligands is, however, still a matter of debate.

摘要

兔血红素结合蛋白C末端结构域和猪成纤维细胞胶原酶全长结构域的结构显示出一种具有假四重对称性的常见β-螺旋桨折叠。然而，这些类血红素结合蛋白结构域与靶蛋白和配体之间的相互作用仍存在争议。