人前列腺癌组织纤连蛋白水平作为一种肿瘤标志物。
Tissue fibronectin levels of human prostatic cancer, as a tumor marker.
作者信息
Sönmez H, Süer S, Karaarslan I, Baloğlu H, Kökoğlu E
机构信息
Department of Biochemistry, Cerrahpaşa Faculty, University of Istanbul, Turkey.
出版信息
Cancer Biochem Biophys. 1995 Nov;15(2):107-10.
In this study, tissue fibronectin levels have been assayed in human prostatic cancer, benign prostatic hyperplasia and normal prostatic tissue. The mean tissue fibronectin levels for prostatic cancer, benign prostatic hyperplasia and normal groups were found to be 20.22 +/- 8.66 micrograms/mg protein and 11.77 +/- 6.74 micrograms/mg protein, respectively. In the malignant group, the mean fibronectin concentrations, appeared to be significantly higher than normal, (p < 0.05). On the other hand, fibronectin levels of benign prostatic hyperplasia were found to be statistically insignificant in comparison to the normal group (p > 0.05).
在本研究中，已对人类前列腺癌、良性前列腺增生和正常前列腺组织中的组织纤连蛋白水平进行了测定。前列腺癌组、良性前列腺增生组和正常组的组织纤连蛋白平均水平分别为20.22±8.66微克/毫克蛋白和11.77±6.74微克/毫克蛋白。在恶性组中，纤连蛋白平均浓度似乎显著高于正常组（p<0.05）。另一方面，与正常组相比，良性前列腺增生的纤连蛋白水平在统计学上无显著差异（p>0.05）。
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