Ataullakhanov F I, Volkova R I, Guriia G T, Sarbash V I
Biofizika. 1995 Nov-Dec;40(6):1320-8.
The growth of fibrin clots in thin blood plasma layers was studied. It was found that the clot growth stops or is strongly retarded if its thickness approaches 0.5 mm. Polymer clots growing toward each other fuse together at distances between the coagulation activation centers less than 1 mm, whereas at distances of about 1.5 mm, the clots are separated by ungrowing flat gaps. In some experiments, successive formation of concentric ring-shaped structures was observed. Around the centers of coagulation initiation, up to 3 fibrin rings separated by areas of uncoagulated plasma were formed. The data agree well with the hypothesis advanced by the authors earlier that blood coagulation is regulated by auto-wave mechanism.
研究了薄血浆层中纤维蛋白凝块的生长情况。发现当凝块厚度接近0.5毫米时，凝块生长会停止或显著减缓。相向生长的聚合物凝块在凝血激活中心之间的距离小于1毫米时会融合在一起，而在距离约为1.5毫米时，凝块之间会被未生长的扁平间隙隔开。在一些实验中，观察到了同心环形结构的连续形成。在凝血起始中心周围，形成了多达3个由未凝血浆区域隔开的纤维蛋白环。这些数据与作者早期提出的血液凝固受自波机制调节的假设非常吻合。
