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[猪(家猪)血液凝固参数的基础值]

[Basic values of blood coagulation parameters in pigs (Sus scrofa domesticus)].

作者信息

Hahn N, Popov-Cenic S, Dorer A

机构信息

Experimentell-chirurgische Abteilung, Medizinischen Fakultät Bonn.

出版信息

Berl Munch Tierarztl Wochenschr. 1996 Jan;109(1):23-7.

PMID:8593155
Abstract

On 23 clinical healthy pigs (2-4 months of age, body weight 13-42 kg) under ketamin-pentobarbital anaesthesia blood plasma coagulation parameters have been investigated. To obtain basic values 26 parameters were measured: number of thrombocytes, parameters of thrombelastogram and resonance-thrombogram, prothrombin time, activated partial thromboplastin time, thrombin time, reptilase time, factors I, II, V, VII, VIII, X, antithrombin III, plasminogen, alpha 1-antitrypsin, alpha 2-antiplasmin, alpha 2-macroglobulin, fibrin degradation products D and E and euglobulin lysis-time. Parameters calculated in percent should be measured against a pig plasma pool. Measurement against a human plasma pool are hardly valid in values higher than 100%. In comparison to man the results indicate modifications of fibrinogenesis and fibrinolysis in pigs.

摘要

在氯胺酮-戊巴比妥麻醉下,对23只临床健康猪(2 - 4月龄,体重13 - 42千克)的血浆凝血参数进行了研究。为获得基础值,测量了26项参数:血小板数量、血栓弹力图和共振血栓图参数、凝血酶原时间、活化部分凝血活酶时间、凝血酶时间、蛇毒凝血酶时间、因子I、II、V、VII、VIII、X、抗凝血酶III、纤溶酶原、α1-抗胰蛋白酶、α2-抗纤溶酶、α2-巨球蛋白、纤维蛋白降解产物D和E以及优球蛋白溶解时间。以百分比计算的参数应以猪血浆混合液为对照进行测量。以人血浆混合液为对照进行测量,在高于100%的值时几乎无效。与人类相比,结果表明猪的纤维蛋白生成和纤维蛋白溶解存在改变。

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