McCrindle B W, Wood M M, Collins G F, Wheatley B, Rowe R D
Hospital for Sick Children, University of Toronto, Ontario.
Can J Cardiol. 1996 Jan;12(1):81-5.
To determine whether Aboriginal Canadians from Manitoba and Ontario have an increased incidence of isolated total anomalous pulmonary venous drainage (TAPVD) and to compare results obtained from two different data sources and time periods.
A nonconcurrent cohort study was undertaken. Incidence rates and relative risk from 'traditional' data sources (cases from medical records data; births from Census, Vital Statistics and Native Registry data for Manitoba and Ontario) from 1972-84 were derived and compared with those from computerized hospital abstract data from Manitoba for 1987-91.
Using traditional data sources an incidence of 0.282/1000 live births was noted in Aboriginals versus 0.062 in non-Aboriginals for a relative risk of 4.6 (95% CI = 2.7-7.7). For Manitoba only the relative risk was 5.8 (95% CI = 2.6-12.8). Using computerized administrative data from Manitoba the relative risk was 5.8 (95% CI = 1.3-25.8).
There is an increased incidence of isolated TAPVD in Aboriginal peoples from Manitoba and Ontario. Further epidemiological investigation is necessary to determine the nature of this association.
确定来自曼尼托巴省和安大略省的加拿大原住民孤立性完全性肺静脉异位引流（TAPVD）的发病率是否增加，并比较从两个不同数据源和时间段获得的结果。
进行了一项非同期队列研究。得出1972 - 1984年“传统”数据源（病历数据中的病例；曼尼托巴省和安大略省人口普查、生命统计和原住民登记数据中的出生数据）的发病率和相对风险，并与1987 - 1991年曼尼托巴省计算机化医院摘要数据的发病率和相对风险进行比较。
使用传统数据源，原住民的发病率为0.282/1000活产，非原住民为0.062，相对风险为4.6（95%可信区间 = 2.7 - 7.7）。仅针对曼尼托巴省，相对风险为5.8（95%可信区间 = 2.6 - 12.8）。使用曼尼托巴省的计算机化管理数据，相对风险为5.8（95%可信区间 = 1.3 - 25.8）。
来自曼尼托巴省和安大略省的原住民中孤立性TAPVD的发病率增加。需要进一步进行流行病学调查以确定这种关联的性质。
