多巴胺激动剂及其与其他神经递质系统的相互作用。
Dopamine agonists and interaction with other neurotransmitter systems.
作者信息
Maj J
出版信息
Naunyn Schmiedebergs Arch Pharmacol. 1977;297 Suppl 1:S53-4. doi: 10.1007/BF00587777.
PMID:859655
Abstract
Studies on the interaction of two dopamine (DA) agonists (selected as most specific): apomorphine (APO) and 1,3-dimethyl-5-aminoadamantane (DMAA) with serotonin (5-HT) and noradrenaline (NA) brain systems have revealed that the drugs induce the activation of 5-HT and NA neurons in an indirect way (via primary DA stimulation). These interactions are relevant for some pharmacological effects of DA agonists.
摘要
对两种多巴胺（DA）激动剂（被选为最具特异性的）：阿扑吗啡（APO）和1,3 - 二甲基 - 5 - 氨基金刚烷（DMAA）与血清素（5 - HT）和去甲肾上腺素（NA）脑系统相互作用的研究表明，这些药物以间接方式（通过初级DA刺激）诱导5 - HT和NA神经元的激活。这些相互作用与DA激动剂的某些药理作用相关。
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