Martínez Díaz-Guerra G, Rigopoulou D, Gómez I, Fernández-Salas M C, León M, Hawkins F
Servicio de Endocrinología y Nutrición, Hospital Universitario 12 de Octubre, Madrid.
Rev Clin Esp. 1995 Dec;195(12):849-52.
An ectopic Cushing syndrome (CS) caused by a medullary thyroid carcinoma (MTC) is an exceptional observation. Two patients are here reported with metastatic MTC, who developed CS two years after the thyroid cancer was diagnosed. A review is also made of clinical and biochemical characteristics of cases with MTC associated with ectopic CS reported in the literature and it is concluded that the cortico-adrenal function in follow-up should be monitored in patients with this type of cancer.
由甲状腺髓样癌(MTC)引起的异位库欣综合征(CS)是一种罕见的情况。本文报告了两名患有转移性MTC的患者,他们在甲状腺癌确诊两年后出现了CS。本文还对文献中报道的与异位CS相关的MTC病例的临床和生化特征进行了综述,并得出结论,对于这类癌症患者,应在随访中监测其肾上腺皮质功能。