Serial transplantation in SCID mice of an epidermodysplasia verruciformis-associated squamous cell carcinoma without alteration of its histological and virological features.
作者信息
Adachi A, Kiyono T, Taguchi O, Ohashi M, Ishibashi M
机构信息
Laboratory of Viral Oncology, Research Institute, Aichi Cancer Center, Nagoya 464, Japan.
出版信息
Virology. 1996 Mar 1;217(1):380-3. doi: 10.1006/viro.1996.0127.
PMID:8599226
Abstract
An epidermodysplasia verruciformis-associated squamous cell carcinoma was xenografted to a SCID mouse, and the resultant tumor was transplanted through mice for 10 generations. Histological and virological features, with replication of about a thousand copies of the papillomavirus DNA, were the same in both the original carcinoma and the transplanted tumors.
摘要
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